January , 2019
Anal fissures are a common anorectal condition, occurring in roughly 1 in 1000 people per year. It is more common in women than in men, and in younger people (less than 50 years of age) than in the elderly. It is often associated with constipation, diarrhea, inflammatory bowel disease, and obesity. While common, anal fissures are easy to treat with lifestyle changes and compounded medications.
Ketotifen is a drug used worldwide for the treatment of allergic conditions, most commonly asthma. While the oral tablet form is commercially available in other countries, it is only available in the United States through compounding pharmacies.