Sirolimus Topical Cream Compounded

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sirolimus-topical

Sirolimus is an immunosuppressant and anti-cancer drug known as an mTOR Kinase Inhibitor. By inhibiting a protein in cells known as mammalian target of rapamycin (mTOR), it helps to suppress the growth and reproduction of cancer cells and other rapidly growing cells in the body. When taken orally, sirolimus is used to treat cancers or conditions where the immune system needs to be suppressed, such as in lymphangioleiomyomatosis or organ transplants. However, when compounded into an ointment or gel, it can be applied topically for more local action to manage angiofibromas due to tuberculosis sclerosis.

Sirolimus Topical Compounded
Sirolimus Topical Compounded
 

This medication requires a prescription.

To process your order we will require a prescription from you or your Prescriber. We will only compound and dispense upon receipt of a valid patient specific prescription. Please note that our compounds are exclusively provided for individual patient and are not for office use.

  • Your prescriber can mail or fax in the prescription
  • You can mail in the original prescription
  • We can contact your prescriber for you
  • You can transfer your prescription from another pharmacy

Please click here to start the process.

 

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Sirolimus is an immunosuppressant and anti-cancer drug known as an mTOR Kinase Inhibitor. By inhibiting a protein in cells known as mammalian target of rapamycin (mTOR), it helps to suppress the growth and reproduction of cancer cells and other rapidly growing cells in the body.

How is Sirolimus Used?

Sirolimus is usually given by mouth in tablet or liquid form. However, it can be compounded into topical gels and creams to treat skin abnormalities due to tuberculosis sclerosis.

What is Sirolimus Used for?

When taken orally, sirolimus is used to treat cancers or conditions where the immune system needs to be suppressed, such as in lymphangioleiomyomatosis or organ transplants. However, when compounded into an ointment or gel, it can be applied topically for more local action to manage angiofibromas due to tuberculosis sclerosis.

Side Effects and Important Information

The most common side effect of topical sirolimus is itching or burning after application. Sirolimus is poorly absorbed through the skin into the bloodstream, so systemic side effects are minimal.

If you experience any side effects when using sirolimus, contact your doctor right away. Talk to your pharmacist or doctor if you are taking any other medications, as sirolimus may interact with other medications. Use the medication as prescribed by your doctor. The information provided is not intended to cover all possible uses. This information is generalized and not intended as specific medical advice. If you have questions about the use of your prescription, please contact your prescriber.

References

  1. Madke B. Topical rapamycin (sirolimus) for facial angiofibromas. Indian Dermatol Online J. 2013 Jan-Mar;4(1):54-57.
  2. Sirolimus. Drug Facts and Comparisons. eFacts [online]. 2020. Available from Wolters Kluwer Health, Inc. Accessed July 15, 2020.

Sirolimus

Consult your prescriber.

This is a compounded medication specifically made for you based on a prescription from your licensed physician.

Troches and suppositories require refrigeration (ice packs) and will incur an extra charge of $19.95 per order.

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