Androgenetic alopecia (AGA), also known as male pattern baldness, is the most common cause of hair loss in men, affecting about 80% of Caucasian males. It is characterized by hair follicles that gradually decrease in size, leading to baldness over time. AGA is usually the result of a genetic predisposition; however, evidence shows that the cause may also be androgen-related. Dihydrotestosterone (DHT) is the primary androgen involved in AGA and men affected by this condition will have increased serum concentrations of DHT.
Flucytosine is an oral antifungal agent that is used with amphotericin B for serious Candida and Cryptococcus infections. It works by penetrating fungal cells and interfering with fungal RNA and protein synthesis. However, it is generally used second-line and its use is limited by its toxicities. Flucytosine should be used with extreme caution in patients with kidney dysfunction and dose adjustments are required. It should also be used with caution in patients with bone marrow depression, hematologic disease, or who have been treated with radiation or drugs that suppress the bone marrow.
Alopecia commonly referred to as hair loss is a condition that affects the majority of the population. It is more prevalent in males; about 30% of men experience hair loss by the age of 30, 50% by the age of 50 and increases 80% by the age of 70. It is less prevalent in females and about 40-50% of women experience hair loss by the age of 70.
Estrogens are a group of hormones produced primarily by the ovaries in women. They can also be produced by the adrenal gland and fat tissue in smaller quantities. It is considered a female hormone, but the testes in men also produce it in very small quantities and contribute to the development of male reproductive organs. It is referred to as a sex hormone as it mainly targets and is produced by the reproductive organs.
Compounded medications are made for each individual or pet who provides a prescription from a physician, veterinarian or other medical professionals. These special medications are formulated for a particular patient rather than for any patient who requires the prescription drug. You might wonder why compounded medications can help you to live a healthier life, and here are six reasons for ordering these prescription drugs from a compounding pharmacy.
It is important to follow the directions provided by the health care provider on how to take the drug to ensure you receive maximum clinical benefit. Compounding of certain medications allows them to be administered in alternate route(s) that are not offered commercially. A compounding pharmacist can work with your doctor to see what options are available.
Like humans, pets can suffer from hormonal changes and disorders as they age. These can cause them to act strangely and change in appearance. One of the most common of these disorders is Cushing's disease. While rare in humans (1-2 cases/million people per year), Cushing's is quite common in pets, particularly in dogs, occurring in 1-2 out of every 1000 dogs per year.
Treatment for cognitive disorders is a growing field in the world of medicine. As we learn more about how the brain works, new drugs are made to manage the effects of the various diseases and disorders of the brain. One of these new drugs is Synapsin®, a dietary supplement made by pharmacist Jim LaValle to promote neurologic and cognitive health.
Anal fissures are a common anorectal condition, occurring in roughly 1 in 1000 people per year. It is more common in women than in men, and in younger people (less than 50 years of age) than in the elderly. It is often associated with constipation, diarrhea, inflammatory bowel disease, and obesity. While common, anal fissures are easy to treat with lifestyle changes and compounded medications.
Ketotifen is a drug used worldwide for the treatment of allergic conditions, most commonly asthma. While the oral tablet form is commercially available in other countries, it is only available in the United States through compounding pharmacies.