Trilostane for Your Furry Friend: Treating Cushing's Disease in Pets
Like humans, pets can suffer from hormonal changes and disorders as they age. These can cause them to act strangely and change in appearance. One of the most common of these disorders is Cushing's disease. While rare in humans (1-2 cases/million people per year), Cushing's is quite common in pets, particularly in dogs, occurring in 1-2 out of every 1000 dogs per year.
Cushing’s Disease and Compounded Trilostane Dogs can suffer from endocrine (hormonal) diseases much like people. Cushing’s disease (hyperadrenocorticism or HAC) is an endocrine disorder, in which dogs produce too much cortisol hormone. 80% of dogs with Cushing’s disease have the pituitary-dependent form, while the remaining are affected by an adrenal gland tumor. Cushing’s disease affects the multiple functions throughout the dog’s entire body.
CareFirst Pharmacy is proud to bring custom-compounded theophylline in flavored, 4-way FlexDose tablets. If your veterinarian has prescribed theophylline for your pet, we are happy to provide an easy way to get just the right dose. What is Theophylline? Theophylline is a phosphodiesterase inhibitor drug and bronchodilator. It is mainly used in dogs and cats with respiratory diseases. It directly relaxes muscles within the bronchi of the lungs and also in the pulmonary blood vessels. Theophylline can cause stimulation of the respiratory centers in the brain and has a mild diuretic effect, which may make it a helpful drug in managing congestive heart failure (CHF) in certain pets.
Heart medication specifically for dogs may seem unusual, but it is far from uncommon. If your dog suffers from a heart condition, your veterinarian may have prescribed pimobendan. What is pimobendan? Pimobendan is a PDE3 (phosphodiesterase III) inhibitor, which increases cardiac contractility while dilating arterioles. In the simplest terms, it helps to relax blood vessels, thus lowering blood pressure and helping the heart to pump blood properly. How can pimobendan help my dog? Pimobendan is a medication that is prescribed for a very specific heart problem: congestive heart failure (CHF) secondary to myxomatous mitral valve disease (MMVD). Pimobendan is not currently recommended for dogs with dilated cardiomyopathy (DCM) or hypertropic cardiomyopathy (HCM). Overall, dogs that take pimobendan tend to have a longer survival time and feel better than dogs with the same condition that do not take pimobendan.
Female Canine Incontinence
Use of Diethylstilbestrol (DES) for therapeutic purposes Urinary incontinence (UI) is defined as the involuntary loss of urine during the filling phase of the bladder . At this time, there are many suspected factors contributing to the problem. Nevertheless, urinary sphincter mechanism incompetence (USMI) after spaying is the most common micturition disorder, and its medical treatment is normally successful. The underlying mechanism is not fully understood. But, we do know that hormonal changes can induce structural and functional alterations in the bladder, as well as in the urethra composition. The proposed predispositions to incontinence that follows neutering including gender, breed, body weight, obesity, tail docking, spaying technique (ovariectomy and ovariohysterectomy) and morphology or position of neck of the bladder and urethral length, have all been investigated